Role of vitamin C infusion in postoperative mechanically ventilated neonates with sepsis: a randomized controlled trial.
- 2025-11-29
- RCT
- European journal of pediatrics 184(12)
- Asmaa Mahmoud Elmesiry
- Mai Rabie Elsheikh
- Khalid Mohamed Elshimy
- Amany Mohamed Abotaleb
- PubMed: 41315087
- DOI: 10.1007/s00431-025-06625-4
- High evidence
- Infants
SpO2/FiO2 did not change across groups at baseline and 24 h but were considerably higher in the Vitamin C group at 72 h and 120 h.
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes
- Dose
- 0.5 g/kg loading dose followed by a maintenance dose of 0.5 g/kg/h over 6 h, continued for 7 to 10 days