Vitamin C and Increased L-Arginine to ADMA Ratio

• Effects of l-Arginine Plus Vitamin C Supplementation on l-Arginine Metabolism in Adults with Long COVID: Secondary Analysis of a Randomized Clinical Trial.

  • 2023-03-07
  • RCT
  • International journal of molecular sciences 24(6)
  • • Riccardo Calvani
    • Jacopo Gervasoni
    • Anna Picca
    • Francesca Ciciarello
    • Vincenzo Galluzzo
    • Hélio José Coelho-Júnior
    • Clara Di Mario
    • Elisa Gremese
    • Sara Lomuscio
    • Anna Maria Paglionico
    • Lavinia Santucci
    • Barbara Tolusso
    • Andrea Urbani
    • Federico Marini
    • Emanuele Marzetti
    • Francesco Landi
    • Matteo Tosato

  • PubMed: 36982151
  • DOI: 10.3390/ijms24065078

  2 Insights on

  • Increased L-Arginine to ADMA Ratio

  • High evidence
  • Rigorous Journal
  • Clinical

  After 28 days of l-arginine plus vitamin C supplementation, serum l-arginine concentrations and l-arginine/ADMA increased significantly compared with placebo.

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes