High-dose Oral Vitamin C Supplementation and Acute Pain Control Following Laparoscopic Cholecystectomy: A Randomized Controlled Study.
- 2026-04
- RCT · n = 320
- Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses 41(2)
- Yoonyoung Choi
- Tae Ho Hong
- PubMed: 41042187
- DOI: 10.1016/j.jopan.2025.06.008
- High evidence
- Large Human Trial
- Clinical
NRS scores and amount of pethidine consumption at each time point (operation day, postoperative day 1, and postoperative day 2) were not significantly different between the two groups.
- Effect
- Neutral
- Effect size
- Small
- Significant
- No
- Dose
- three 1 g tablets, four times each, both before and after surgery