Vitamin C Supplementation Accelerates Healing in Diabetic Foot Ulcers: Insights From a Systematic Review of Clinical Evidence.
- 2026-05-20
- Review
- Cureus 18(5)
- Mohammed A Saad
- Durgam Sathyam
- Sravanthi Koora
- Satyanarayana Kottireddy
- PubMed: 42326242
- DOI: 10.7759/cureus.109297
- Low evidence
- Clinical
Observational data demonstrated that low serum vitamin C (<23 µmol/L) was strongly correlated with delayed healing, severe ulceration, and increased risk of amputation.
- Effect
- Beneficial
- Effect size
- Large
- Significant
- Yes
- Dose
- 500-1000 mg/day