Vitamin C and Reduced Fluid Requirement

• Intravenous vitamin C in critically ill adult patients with burns: An integrative review.

  • 2025-06
  • Review
  • Nutrition (Burbank, Los Angeles County, Calif.) 134
  • • Juan Novoa
    • Gil Hardy
    • Ignacio Aramendi
    • William Manzanares

  • PubMed: 40081106
  • DOI: 10.1016/j.nut.2025.112728

  5 Insights on

  • Reduced Fluid Requirement

  • Low evidence

  high-dose intravenous vitamin C may reduce fluid requirements, body weight gain, and wound edema, improving gas exchange and renal function in the acute phase after burn injury.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

  Dose

  high-dose intravenous vitamin C

• Vitamin C for all?

  • 2024-05-20
  • Review
  • Current opinion in critical care 30(4)
  • • Angelique de Man
    • Micah T Long
    • Christian Stoppe

  • PubMed: 38841995
  • DOI: 10.1097/mcc.0000000000001161

  6 Insights on

  • Reduced Fluid Requirement

  • Low evidence

  decreased fluid requirements, reduced wound healing time and in-hospital mortality after burns

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

  Dose

  high-dose