Vitamin C and Reduced Melasma Severity

• The Impact of Antioxidants on Vitiligo and Melasma: A Scoping Review and Meta-Analysis.

  • 2023-12-06
  • Meta-Analysis
  • Antioxidants (Basel, Switzerland) 12(12)
  • • Reinhart Speeckaert
    • Vedrana Bulat
    • Marijn M Speeckaert
    • Nanja van Geel

  • PubMed: 38136202
  • DOI: 10.3390/antiox12122082

  2 Insights on

  • Reduced Melasma Severity

  • High evidence
  • Clinical

  For melasma, vitamin C, silymarin, and niacinamide were among those showing promise in reducing pigmentation, with vitamin C displaying significant effects in meta-analysis.

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes