Vitamin C and Reduced Pre-Term Premature Rupture of Membranes

• Efficacy of vitamin C supplementation during pregnancy in the prevention of preterm birth: a systematic review and meta-analysis.

  • 2025
  • Meta-Analysis · n = 567
  • Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia 47
  • • Ana Gabriela Alves Pereira
    • Gabriela Oliveira Gonçalves Molino
    • Ana Clara Felix de Farias Santos
    • Maírla Marina Ferreira Dias
    • Nicole Dos Santos Pimenta
    • Nicole Dos Santos Pimenta
    • Pedro Henrique Costa Matos da Silva

  • PubMed: 40584396
  • DOI: 10.61622/rbgo/2025rbgo1

  6 Insights on

  • Reduced Pre-Term Premature Rupture of Membranes

  • High evidence
  • Clinical

  No significant differences were observed for ... preterm PROM (RR 1.04; 95% CI 0.63, 1.71).

  Effect

  Neutral

  Effect size

  Small

  Significant

  No