Vitamin C and Reduced SOFA Score

• Intravenous Vitamin C in Severe Sepsis: A Systematic Review of Evidence From 2020 to 2025.

  • 2026-01-05
  • Review
  • Cureus 18(1)
  • • Rana Ahmed
    • Shashwat Shetty
    • Muhammad Qaiser Aziz Khan
    • Iqra Kalsoom
    • Shazia Qasim
    • Shair Bahadar Khan
    • Saad Abdullah

  • PubMed: 41658835
  • DOI: 10.7759/cureus.100867

  3 Insights on

  • Reduced SOFA Score

  • Low evidence
  • Clinical

  Results indicate modest physiological benefits, such as transient reductions in Sequential Organ Failure Assessment (SOFA) scores and vasopressor duration

  Effect

  Beneficial

  Effect size

  Small