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Evidence-Based Supplement Research
Evidence-Based Supplement Research

Vitamin C and Reduced Systolic Blood Pressure

Research synthesisModerate evidenceModerate effect4 studies · 4 beneficial · 0 neutral · 0 harmful

Across 4 studies, all reported beneficial effects of vitamin C on reducing systolic blood pressure, with a predominant moderate effect size. Two meta-analyses (the highest-quality evidence) found significant reductions, including an estimated 3.7 mmHg decrease in adults and benefits in individuals with type 2 diabetes. Studies ranged from 40 days in one trial to meta-analyses without specified durations, with a median study duration of 40 days, suggesting effects may appear within weeks.

  • Studied populations: individuals with type 2 diabetes, adults, young healthy participants, heat-exposed workers

Caveats: Evidence base is small (only 4 studies) — conclusions should be considered preliminary. Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). Doses varied widely or were not specified in most studies, so no clear effective dose range can be determined; one trial used 130 mg/day. Most studies lacked form data, so no form-specific conclusions can be drawn.

Generated Jun 11, 2026
Doses used in studies
  • mg/day: 130 (median 130, IQR 130130) 1 study
Time to effect
Median: 5.7 weeks · IQR 5.7 weeks5.7 weeks · Range 5.7 weeks5.7 weeks — Reported in 1 of 4 studies
4 of 4 papers
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