Vitamin C and Reduced Systolic Blood Pressure

• Effects of Vitamin C and/or E Supplementation on Glycemic Control and Cardiovascular Risk Factors in Type 2 Diabetes: A Systematic Review and Subgroup Meta-analysis.

  • 2025-08-05
  • Meta-Analysis · n = 1,425
  • Nutrition reviews 84(2)
  • • Jerónimo Aragón-Vela
    • Jesús R Huertas
    • Rafael A Casuso

  • PubMed: 41521729
  • DOI: 10.1093/nutrit/nuaf133

  2 Insights on

  • Reduced Systolic Blood Pressure

  • High evidence
  • Clinical

  A significant reduction in systolic blood pressure was observed only with vitamin C and combined vitamin C + E supplementation.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

• The effect of vitamin C supplementation on blood pressure in adults: an umbrella review of meta-analyses of randomized clinical trials.

  • 2026
  • Meta-Analysis · n = 17
  • Food & function 17(6)
  • • Ali Kosari
    • Hossein Shahinfar
    • Kimia Rostampour
    • Seyedeh Ghazal Mirhosseini
    • Sepideh Soltani

  • PubMed: 41784995
  • DOI: 10.1039/d5fo03679h

  2 Insights on

  • Reduced Systolic Blood Pressure

  • High evidence
  • Rigorous Journal
  • Adults

  vitamin C supplementation may reduce SBP by approximately 3.7 mmHg

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes