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Evidence-Based Supplement Research
Evidence-Based Supplement Research
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Vitamin C and Reduced Systolic Blood Pressure

Research synthesisModerate evidenceModerate effect3 studies · 3 beneficial · 0 neutral · 0 harmful

Across 3 studies, all reported beneficial effects on systolic blood pressure, with two meta-analyses showing moderate reductions (e.g., ~3.7 mmHg) and one small RCT finding a significant reduction when co-ingested with dietary nitrate. The predominant effect size is moderate. Evidence primarily comes from adults with type 2 diabetes and general adult populations. Doses and forms were not consistently reported across studies.

  • Studied populations: adults, particularly those with type 2 diabetes

Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. Additionally, available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). Doses and forms were not consistently reported, limiting specificity.

Generated May 16, 2026
3 of 3 papers
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