Vitamin D and Improved Complement C3 Level

• Effects of vitamin D supplementation on patients with systemic lupus erythematosus: A systematic review and meta-analysis.

  • 2026-05
  • Meta-Analysis · n = 847
  • Autoimmunity reviews 25(5)
  • • Jiale Lu
    • Qingmiao Zhu
    • Jiaxun Yu
    • Zhuchen Tan
    • Yingxin Kang
    • Qice Sun
    • Ting Zhao

  • PubMed: 41951148
  • DOI: 10.1016/j.autrev.2026.104057

  4 Insights on

  • Improved Complement C3 Level

  • High evidence
  • Clinical

  Significant improvements were also observed in complement component C3 (MD = 14.49, p = 0.03) and C4 (SMD = 2.08, p = 0.04).

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes