Vitamin D and Improved Total Volumetric Bone Mineral Density

• Interim Effects of Zoledronate, Denosumab, or Teriparatide on Bone Microarchitecture in Type 2 Diabetes: A Pilot Trial.

  • 2025-11-03
  • RCT
  • The Journal of clinical endocrinology and metabolism 111(5)
  • • Trupti N Prasad
    • Rimesh Pal
    • Sanjay K Bhadada
    • Sant Ram
    • Veenu Singla
    • Seema Pulami

  • PubMed: 41183496
  • DOI: 10.1210/clinem/dgaf589

  3 Insights on

  • Improved Total Volumetric Bone Mineral Density

  • High evidence
  • Clinical

  Zoledronate improved only tibial total vBMD. Teriparatide significantly improved total and trabecular volumetric BMD...

  Effect

  Neutral

  Effect size

  Small

  Significant

  No

  Dose

  standard of care (calcium/cholecalciferol) – specific dose not stated