Effects of vitamin D3, omega-3 fatty acids and a simple home exercise program on change in physical activity among generally healthy and active older adults: The 3-year DO-HEALTH trial.
- 2025-05
- RCT
- The journal of nutrition, health & aging 29(5)
- Kariem Hussein
- Melanie Kistler-Fischbacher
- Michèle Mattle
- Caroline De Godoi Rezende Costa Molino
- Li-Tang Tsai
- Reto W Kressig
- E John Orav
- José A P Da Sliva
- Bruno Vellas
- René Rizzoli
- Gabriele Armbrecht
- Egli Andreas
- Bess Dawson-Hughes
- Heike A Bischoff-Ferrari
- PubMed: 40054416
- DOI: 10.1016/j.jnha.2025.100528
- High evidence
- Elderly
participants receiving vitamin D3 compared to those receiving no vitamin D3 (Δadjusted means: -7.1 [95% CI -12.7, -1.5] MET h/wk, P = 0.01) showed a decline in PA.
- Effect
- Harmful
- Effect size
- Small
- Significant
- Yes
- Dose
- 2000 IU/d