Vitamin D and Reduced 1,25-Dihydroxyvitamin D to 25-Hydroxyvitamin D Ratio

• Short-Term Effects of Escalating Doses of Cholecalciferol on FGF23 and 24,25(OH)2 Vitamin D Levels: A Preliminary Investigation.

  • 2024-10-23
  • RCT
  • Nutrients 16(21)
  • • Jessica Pepe
    • Luciano Colangelo
    • Roberta Pilotto
    • Viviana De Martino
    • Carla Ferrara
    • Alfredo Scillitani
    • Mirella Cilli
    • Salvatore Minisola
    • Ravinder Singh
    • Cristiana Cipriani

  • PubMed: 39519433
  • DOI: 10.3390/nu16213600

  10 Insights on

  • Reduced 1,25-Dihydroxyvitamin D to 25-Hydroxyvitamin D Ratio

  • High evidence
  • Rigorous Journal
  • Clinical

  A decrease in both the 1,25(OH)2D/25(OH)D and 1,25(OH)2D/24,25(OH)2D ratio (all p < 0.05) was observed in the 600,000 I.U. group.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

  Dose

  600,000 I.U. single oral dose