Vitamin D and Reduced Active Tuberculosis

The incidence of serious adverse events was comparable between the vitamin D and placebo groups (OR: 1.02; 95% CI: 0.76-1.38; p = 0.87), and none of the serious events were attributed to vitamin D supplementation.

In conclusion, vitamin D supplementation does not significantly reduce the risk of tuberculosis infection or progression to active tuberculosis, although it is safe and well tolerated.