Vitamin D and Reduced Alzheimer Disease Incidence

• The Effect of Vitamin D3 Supplementation on the Incidence of Diagnosed Dementia Among Healthy Older Adults-The Finnish Vitamin D Trial.

  • 2025-04-17
  • RCT · n = 550
  • The journals of gerontology. Series A, Biological sciences and medical sciences 80(7)
  • • Eija Lönnroos
    • Maija Ylilauri
    • Christel Lamberg-Allardt
    • JoAnn E Manson
    • Tarja Nurmi
    • Matti Uusitupa
    • Ari Voutilainen
    • Sari Hantunen
    • Tomi-Pekka Tuomainen
    • Jyrki K Virtanen

  • PubMed: 40243375
  • DOI: 10.1093/gerona/glaf077

  2 Insights on

  • Reduced Alzheimer Disease Incidence

  • High evidence
  • Large Human Trial
  • Clinical

  Of the diagnoses, 29 were Alzheimer's disease, without statistically significant differences in the event rates between the 3 arms.

  Effect

  Neutral

  Effect size

  Small

  Significant

  No

  Dose

  3,200 IU/day