Vitamin D and Reduced Bone Fracture

• Calcium, vitamin D, or combined supplementation to prevent fractures and falls: systematic review and meta-analysis.

  • 2026-05-20
  • Meta-Analysis · n = 9,067
  • BMJ (Clinical research ed.) 393
  • • Olivier Massé
    • Claudia Mei Mercurio
    • Sébastien Dupuis
    • Maya Al Sahwi
    • Alexandra Arruda
    • Gabriel Dallaire
    • Katherine Desforges
    • Nicolas Dugré
    • David Williamson

  • PubMed: 42161415
  • DOI: 10.1136/bmj-2025-088050

  6 Insights on

  • Reduced Bone Fracture

  • High evidence
  • Clinical

  combined supplementation (15 trials, 51 126 participants; 0.91, 0.84 to 0.99; high certainty)

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes