Vitamin D and Reduced Bone Mineral Density

• Effect of supplemental vitamin D3 on bone mineral density: a systematic review and meta-analysis.

  • 2022-10-29
  • Meta-Analysis
  • Nutrition reviews 81(5)
  • • Elham Kazemian
    • Ali Pourali
    • Fatemeh Sedaghat
    • Mehrdad Karimi
    • Vahid Basirat
    • Zohreh Sajadi Hezaveh
    • Sayed Hossein Davoodi
    • Michael F Holick

  • PubMed: 36308775
  • DOI: 10.1093/nutrit/nuac068

  2 Insights on

  • Reduced Bone Mineral Density

  • High evidence

  Vitamin D3 supplementation significantly decreased BMD at both proximal and distal forearm (SMD = -0.16; 95%CI, -0.26 to -0.06)

  Effect

  Harmful

  Effect size

  Small

  Significant

  Yes