Vitamin D and Reduced CCL20 Level

Doses used in studies

IU/day: 200,000 (median 200,000, IQR 200,000–200,000) — 1 study

Time to effect

Median: 6 weeks · IQR 6 weeks–6 weeks · Range 6 weeks–6 weeks — Reported in 1 of 1 study

1 of 1 paper

Vitamin D3 and deconvoluting a rash.

2023-01-24
RCT · n = 28
JCI insight 8(2)
- Madison K Ernst
- Spencer T Evans
- Jose-Marc Techner
- Robert M Rothbaum
- Luisa F Christensen
- Ummiye Venus Onay
- Dauren Biyashev
- Michael M Demczuk
- Cuong V Nguyen
- Kord S Honda
- Thomas S McCormick
- Lam C Tsoi
- Johann E Gudjonsson
- Kevin D Cooper
- Kurt Q Lu

PubMed: 36692020
DOI: 10.1172/jci.insight.163789

5 Insights on

Reduced CCL20 Level

High evidence
Adults

Multi-omic and pathway analyses revealed a 3-biomarker signature (CCL20, CCL2, CXCL8) unique to exaggerated responders that is suppressed by cholecalciferol

Effect: Beneficial
Effect size: Small
Significant: Yes
Dose: 200,000 IU