Vitamin D and Reduced Celiac Disease Risk

• Genetic predisposition to serum 25 hydroxyvitamin D concentrations does not influence the risk of decreasing celiac disease in European ancestry: Evidence from meta-analysis and Mendelian randomization.

  • 2026-07-03
  • Meta-Analysis · n = 4
  • Medicine 105(27)
  • • Mahdi Akbarzadeh
    • Fahimeh Haghighatdoost
    • Amirhossein Ataei Kachouei
    • Alireza Soleymani Taloubaghi
    • Taha Rafiei
    • Soheil Rahmati
    • Yasamin Jiani
    • Amir Hesam Saeidian
    • Fereidoun Azizi
    • Mehdi Hedayati
    • Maryam S Daneshpour
    • Mohammad Rafiei
    • Danial Habibi

  • PubMed: 42410823
  • DOI: 10.1097/md.0000000000049587

  1 Insight on

  • Reduced Celiac Disease Risk

  • High evidence

  Both the meta-analysis and Mendelian randomization analysis indicate that vitamin D levels have no effect on the risk of developing celiac disease.

  Effect

  Neutral

  Effect size

  Small

  Significant

  No