Vitamin D and Reduced Exacerbation Frequency

• The Role and Clinical Significance of Vitamin D in Chronic Obstructive Pulmonary Disease.

  • 2025-06-23
  • Review
  • International journal of chronic obstructive pulmonary disease 20
  • • Mengqing Sun
    • Yang Qian
    • Chenting Cai
    • Jiaqian Zhang
    • Ruonan Qi
    • Hongying Ma
    • Qunli Ding
    • Shanshan Wang
    • Dan Lv

  • PubMed: 40585424
  • DOI: 10.2147/copd.s520795

  3 Insights on

  • Reduced Exacerbation Frequency

  • Low evidence

  Clinical observational studies have demonstrated significant associations between vitamin D deficiency and increased exacerbation frequency, accelerated lung function decline, and elevated mortality risk.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes