Vitamin D and Reduced Fecal Calprotectin

Doses used in studies

IU single-dose: 2,000–800,000 (median 401,000, IQR 2,000–800,000) — 1 study

Time to effect

Median: 12.2 months · IQR 12.2 months–12.2 months · Range 12.2 months–12.2 months — Reported in 1 of 1 study

1 of 1 paper

Daily Vitamin D3 Versus Stoss Vitamin D3 for Correction of 25OHD Deficiency in Children with Inflammatory Bowel Disease, a Randomised Controlled Trial.

2025-02-28
RCT · n = 74
Digestive diseases and sciences 70(5)
- Jonathan E M O'Donnell
- Steven T Leach
- Nerissa L Bowcock
- Siying Chen
- Nitin Gupta
- Kevin Jiang
- Robert N Lopez
- Rachel Messenger
- Lily Nahidi
- Amanda Shapiro
- Andrew S Day
- Daniel A Lemberg

PubMed: 40021606
DOI: 10.1007/s10620-025-08913-3

12 Insights on

Reduced Fecal Calprotectin

High evidence
Rigorous Journal
Clinical

There was no difference in biochemical, stool or clinical markers between groups at any time point, nor was there any correlation between 25OHD level and calprotectin

Effect: Neutral
Effect size: Small
Significant: No
Dose: 2000 IU daily or 400,000 IU (3-12 years) or 800,000 IU (>12 years) single dose