Vitamin D and Reduced Homeostatic Model Assessment-Insulin Resistance Index

• A meta-analysis of the effects of vitamin D supplementation on endocrine metabolic and inflammatory markers in patients with polycystic ovarian syndrome.

  • 2026-01-02
  • Meta-Analysis
  • Medicine 105(1)
  • • Baohua Wu
    • Jun Yao

  • PubMed: 41496027
  • DOI: 10.1097/md.0000000000046892

  12 Insights on

  • Reduced Homeostatic Model Assessment-Insulin Resistance Index

  • High evidence
  • Clinical

  vitamin D reduces the homeostatic model assessment-insulin resistance index (HOMA-IR) (MD = -0.47; 95% CI: -0.66 to -0.28; P < .00001)

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes