Vitamin D and Reduced Interleukin-1 Beta Level

Doses used in studies

IU single-dose: 300,000 (median 300,000, IQR 300,000–300,000) — 1 study

1 of 1 paper

Investigating the Effect of High-Dose Vitamin D3 Administration on Inflammatory Biomarkers in Patients with Moderate to Severe Traumatic Brain Injury: A Randomized Clinical Trial.

2024-10-01
RCT
Iranian journal of medical sciences 49(10)
- Farnoosh Masbough
- Mehran Kouchek
- Mohsen Koosha
- Sara Salarian
- Mirmohammad Miri
- Masoomeh Raoufi
- Niloufar Taherpour
- Saied Amniati
- Mohammad Sistanizad

PubMed: 39449769
DOI: 10.30476/ijms.2023.99465.3156

6 Insights on

Reduced Interleukin-1 Beta Level

High evidence
Clinical

significant decrease in IL-1β levels (-2.71±3.02, in the intervention group: P=0.001 vs. -0.14±3.70, in the control group: P=0.876) 3 days after the intervention

Effect: Beneficial
Effect size: Moderate
Significant: Yes
Dose: single intramuscular dose of 300,000 IU