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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Vitamin D and Reduced Platelet Aggregation

Doses used in studies

IU/day: 4,000–300,000 (median 152,000, IQR 4,000–300,000) — 1 study

Time to effect

Median: 3 months · IQR 3 months–3 months · Range 3 months–3 months — Reported in 1 of 1 study

1 of 1 paper

Effect of oral versus parenteral vitamin D3 supplementation on nuclear factor-κB and platelet aggregation in type 2 diabetic patients.
- 2023-11-01
- RCT
- Canadian journal of physiology and pharmacology 101(11)
- - Esraa Habiba
  - Samia Ali
  - Yehia Ghanem
  - Ola Sharaki
  - Wafaa Hewedy
- PubMed: 37721213
- DOI: 10.1139/cjpp-2022-0359
3 Insights on
- Reduced Platelet Aggregation
- High evidence
- Clinical
Oral and parenteral treatment were also able to decrease NF-κB level, platelet aggregation, and platelet calcium content.
Effect
Beneficial
Effect size
Small
Significant
Yes
Dose
4000 IU/day orally, 50000 IU/week orally, or 300000 IU single parenteral dose, for 3 months