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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Vitamin D and Reduced Senescence-Associated Beta-Galactosidase Activity

Doses used in studies

IU/day: 1,000 (median 1,000, IQR 1,000–1,000) — 1 study

Time to effect

Median: 8 weeks · IQR 8 weeks–8 weeks · Range 8 weeks–8 weeks — Reported in 1 of 1 study

1 of 1 paper

Co-administration of vitamin D and N-acetylcysteine to modulate immunosenescence in older adults with vitamin D deficiency: a randomized clinical trial.
- 2025-05-12
- RCT
- Frontiers in immunology 16
- - Samira Rastgoo
  - Katayoun Pourvali
  - Seyed Ahmad Raeissadat
  - Ghazaleh Eslamian
  - Hamid Zand
- PubMed: 40421021
- DOI: 10.3389/fimmu.2025.1570441
6 Insights on
- Reduced Senescence-Associated Beta-Galactosidase Activity
- High evidence
- Clinical
supplementation with D5N and D5 significantly ... decreased SA-β-gal activity compared to the D1 group.
Effect
Beneficial
Effect size
Moderate
Significant
Yes
Dose
5000 IU daily