Skip to main content
Evidence-Based Supplement Research
Evidence-Based Supplement Research
Pillser
Search
Sign UpLog In

Vitamin D and Reduced Systolic Blood Pressure

Research synthesisLow evidenceSmall effect3 studies · 2 beneficial · 1 neutral · 0 harmful

Across 3 studies, 2 reported small beneficial effects of vitamin D on reducing systolic blood pressure, while 1 found no significant effect. A 2025 meta-analysis showed a small but statistically significant reduction (MD: -2.83 mmHg), and a review in obese youths with low baseline vitamin D found a moderate beneficial effect. The evidence base is small and mixed, with benefit potentially limited to those with vitamin D deficiency or specific populations.

  • Effective dose range: 4000 IU/day
  • Studied populations: obese youths with baseline 25(OH)D <20 ng/mL and modest systemic inflammation

Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. Benefit was observed primarily in a deficient population with obesity; effects may not generalize to those with sufficient vitamin D levels or without inflammation. One meta-analysis found no significant effect with vitamin D2, suggesting form may influence outcomes.

Generated May 12, 2026
Doses used in studies
  • IU/day: 4,000 (median 4,000, IQR 4,000–4,000) — 1 study
3 of 3 papers
Back to top