Vitamin D and Reduced Total Testosterone Level

• The Association Between Vitamin D and Polycystic Ovary Syndrome (PCOS) in Women: A Systematic Review.

  • 2026-03-19
  • Systematic Review · n = 1,063
  • Nutrients 18(6)
  • • Batoul Jaafar
    • Nour Chami
    • Mohamad Tlais
    • Maria Matar
    • Nazih Obeid
    • Nadia Taha
    • Karim El Haddad
    • Jessica Abou Chaaya
    • Sami Azar

  • PubMed: 41901143
  • DOI: 10.3390/nu18060968

  7 Insights on

  • Reduced Total Testosterone Level

  • High evidence
  • Rigorous Journal
  • Clinical

  Observational studies demonstrated inverse associations between serum 25(OH)D levels and insulin resistance, body mass index (BMI), and leptin, but not with total testosterone.

  Effect

  Neutral

  Effect size

  Small

  Significant

  No