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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Vitamin D and Reduced Undercarboxylated-to-Carboxylated Osteocalcin Ratio

Doses used in studies

mcg/day: 5 (median 5, IQR 5–5) — 1 study

Time to effect

Median: 12.2 months · IQR 12.2 months–12.2 months · Range 12.2 months–12.2 months — Reported in 1 of 1 study

1 of 1 paper

The efficacy of vitamin K2 and calcitriol combination on thalassemic osteopathy.
- 2013-11
- Clinical Trial
- Journal of pediatric hematology/oncology 35(8)
- - Mehmet A Ozdemir
  - Kenan Yilmaz
  - Ummuhan Abdulrezzak
  - Sebahattin Muhtaroglu
  - Turkan Patiroglu
  - Musa Karakukcu
  - Ekrem Unal
- PubMed: 24136015
- DOI: 10.1097/mph.0000000000000040
2 Insights on
- Reduced Undercarboxylated-to-Carboxylated Osteocalcin Ratio
- Moderate evidence
- Clinical
We also found a decrease in the ratio of undercarboxylated osteocalcin to carboxylated osteocalcin, however, this was not found to be significant.
Effect
Neutral
Effect size
Small
Significant
No
Dose
5 mcg/day