Skip to main content
Evidence-Based Supplement Research
Evidence-Based Supplement Research
Pillser
Search
Sign UpLog In

Vitamin D and Reduced Uric Acid Levels

Research synthesisLow evidenceSmall effect3 studies · 0 beneficial · 3 neutral · 0 harmful

Across 3 studies, findings were consistently neutral with a small predominant effect size on uric acid levels; 1 of 3 studies reported a statistically significant finding. The median study duration was approximately 147 days (about 21 weeks), though effects were not detected for the outcome of interest. Evidence is preliminary due to the small number of studies and limited direct assessment of uric acid as a primary outcome.

  • Studied populations: women with PCOS, women of childbearing age with vitamin D insufficiency, and hypertensive obese OSA patients

Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. Many of the included studies did not reach statistical significance — effect may be smaller than the predominant direction suggests. The one significant finding came from an observational systematic review and was not specific to uric acid (the outcome appears as part of a broader list of parameters), limiting direct inference. No form data was reported across studies.

Generated Jul 12, 2026
Doses used in studies
  • IU/day: 400–800 (median 600, IQR 400–800) — 1 study
Time to effect
Median: 4.9 months · IQR 4.3 months–5.5 months · Range 3.7 months–6.1 months — Reported in 2 of 3 studies
Safety in these studies
3 of 3 papers
Back to top