Efficacy of Vitamin D3 Supplementation in Elevating Circulating 25(OH)D Concentration in Individuals With Chronic Spinal Cord Injury (VitD-SCI): Evidence From a Randomized, Double-Blind, Placebo-Controlled Trial.
- 2025-01
- RCT · n = 42
- Topics in spinal cord injury rehabilitation 31(4)
- Anneke Hertig-Godeschalk
- Martin W G Brinkhof
- Claudio Perret
- Anke Scheel-Sailer
- Joelle L Flueck
- PubMed: 41268138
- DOI: 10.46292/sci24-00077
- High evidence
- Clinical
A dose-response effect on 25(OH)D levels was observed [F(2, 40) = 8.21, P < .001]. In the HD group, 46% of the participants reached sufficient levels.
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes
- Dose
- 24,000 IU once every 4 weeks (medium-dose) or 24,000 IU once every 2 weeks (high-dose)