Vitamin D3 and Increased Spinal Fusion Rate

• Concurrent Treatment with Vitamin K2 and D3 on Spine Fusion in Patients with Osteoporosis-Associated Lumbar Degenerative Disorders.

  • 2021-12-15
  • Clinical Trial
  • Spine 47(4)
  • • Wencan Zhang
    • Le Li
    • Xin Zhou
    • Kunpeng Li
    • Chen Liu
    • Xiangyu Lin
    • Njabulo Lubisi
    • Junfei Chen
    • Haipeng Si

  • PubMed: 34919073
  • DOI: 10.1097/brs.0000000000004309

  1 Insight on

  • Increased Spinal Fusion Rate

  • Moderate evidence
  • Clinical

  At six months postoperatively, complete fusion rates were significantly higher in the VK2+VD3 group than that in the control group (91.18% vs 71.43%, P = 0.036).

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes