Vitamin D3 and Reduced Respiratory Complications

• The effects of nutritional supplementation for children and adolescents with sickle cell disease: A systematic review and meta-analyses.

  • 2025-04
  • Systematic Review · n = 2,058
  • Clinical nutrition (Edinburgh, Scotland) 47
  • • Bruna C Orsi
    • Daniela Gorski
    • Naila E Krul
    • Astrid Wiens
    • Miguel Brito
    • Fernanda S Tonin
    • Roberto Pontarolo

  • PubMed: 40022955
  • DOI: 10.1016/j.clnu.2025.02.016

  5 Insights on

  • Reduced Respiratory Complications

  • High evidence
  • Clinical

  may reduce respiratory complications and length of hospital stay, yet further studies are needed to confirm its significant effects.

  Effect

  Neutral

  Effect size

  Small

  Significant

  No