Vitamin E and Decreased Interleukin-1 Level

• Comparative efficacy of tocotrienol and tocopherol (vitamin E) on atherosclerotic cardiovascular diseases in humans.

  • 2024-05-24
  • Systematic Review
  • JPMA. The Journal of the Pakistan Medical Association 74(6)
  • • Saima Rafique
    • Dilshad Ahmed Khan
    • Kulsoom Farhat
    • Muhammad Asghar Khan
    • Mudassar Noor
    • Mahjabeen Sharif

  • PubMed: 38948984
  • DOI: 10.47391/jpma.9227

  8 Insights on

  • Decreased Interleukin-1 Level

  • High evidence
  • Clinical

  Total anti-oxidant status (TAS) levels raised 22% (p<0.001) and Inflammatory cytokines i.e resistin, interleukin (IL)-1, IL-12, Interferon-gamma were decreased 15-17% (p<0.05-0.01) respectively by tocotrienol.

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes

  Dose

  250 mg/d