Pharmacological treatments for Friedreich ataxia.
- 2026-05-12
- Meta-Analysis · n = 574
- The Cochrane database of systematic reviews 2026(5)
- Shane Lyons
- Mary Kearney
- Michael C Fahey
- Prashant Janjal
- Massimo Pandolfo
- Patricia Patton
- PubMed: 42117563
- DOI: 10.1002/14651858.cd007791.pub5
- High evidence
- Clinical
Meta-analysis of seven studies demonstrated that pharmacological treatment probably makes little or no difference to scores on the ataxia rating scale after 12 months of treatment (SMD 0.02, 95% CI -0.23 to 0.26; I² = 42%; 7 studies, 513 participants; moderate-certainty evidence).
- Effect
- Neutral
- Effect size
- Small
- Significant
- No