Vitamin E and Improved Hepatic Histology

• Vitamin E (300 mg) in the treatment of MASH: A multi-center, randomized, double-blind, placebo-controlled study.

  • 2025-02
  • RCT
  • Cell reports. Medicine 6(2)
  • • Yu Song
    • Wenjing Ni
    • Minghua Zheng
    • Huiping Sheng
    • Jing Wang
    • Shilong Xie
    • YongFeng Yang
    • Xiaoling Chi
    • Jinjun Chen
    • Fangping He
    • Xiaotang Fan
    • Yuqiang Mi
    • Jing Zhang
    • Bingyuan Wang
    • Lang Bai
    • Wen Xie
    • Bihui Zhong
    • Yee Hui Yeo
    • Fajuan Rui
    • Shufei Zang
    • Jie Li
    • Junping Shi

  • PubMed: 39970876
  • DOI: 10.1016/j.xcrm.2025.101939

  4 Insights on

  • Improved Hepatic Histology

  • High evidence
  • Clinical

  29.3% of participants in the vitamin E group achieve the primary outcome compared with 14.1% in the placebo group.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

  Dose

  300 mg/day