Vitamin E and Improved MASH Resolution

• Vitamin E improves serum markers and histology in adults with metabolic dysfunction-associated steatotic liver disease: Systematic review and meta-analysis.

  • 2024-08-16
  • Meta-Analysis
  • Journal of gastroenterology and hepatology 39(12)
  • • Nicholas Ming-Zher Chee
    • Ram Prasad Sinnanaidu
    • Wah-Kheong Chan

  • PubMed: 39150005
  • DOI: 10.1111/jgh.16723

  7 Insights on

  • Improved MASH Resolution

  • High evidence
  • Clinical

  increased MASH resolution with a RR of 1.9 (95%CI, 1.20 to 3.02)

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes

• Efficacy and Safety of Vitamin E in Adults With Metabolic Dysfunction-Associated Steatohepatitis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

  • 2025-07-29
  • Review
  • Cureus 17(7)
  • • Helai Hussaini
    • Manpreet Kaur Dhanjal
    • Rahman Hameed Mohammed Abdul
    • Olaniyi Fadeyi
    • Najeeha A Bhatti
    • Mohammed Qasim Rauf
    • Calvin R Wei
    • Adil Amin

  • PubMed: 40895855
  • DOI: 10.7759/cureus.88949

  4 Insights on

  • Improved MASH Resolution

  • Low evidence
  • Clinical

  MASH resolution showed no statistically significant difference between groups (OR: 1.71, 95% CI: 0.69-4.27)

  Effect

  Neutral

  Effect size

  Small

  Significant

  No

  Dose

  300 to 800 mg daily