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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Vitamin E and Improved Sperm Motility

Doses used in studies

U single-dose: 100 (median 100, IQR 100–100) — 1 study
mg/day: 200 (median 200, IQR 200–200) — 1 study

Time to effect

Median: 2.9 months · IQR 2.9 months–3 months · Range 2.8 months–3 months — Reported in 2 of 2 studies

2 of 2 papers

Effect of Medicago sativa seed powder (Plus vitamin E vs. vitamin E alone) on semen analysis in men with idiopathic infertility: A double blind randomized clinical trial.
- 2024-03
- RCT · n = 60
- Journal of ethnopharmacology 322
- - Azita Sadough Shahmirzadi
  - Hamid Shafi
  - Hoda Shirafkan
  - Zahra Memariani
  - Narjes Gorji
  - Reihaneh Moeini
- PubMed: 38103848
- DOI: 10.1016/j.jep.2023.117606
3 Insights on
- Improved Sperm Motility
- High evidence
- Clinical
percentage of motile sperm changed from ... 39.3 ± 10.1 % to 38.1 ± 12.1% in placebo ... The improvements in M. sativa group are significantly better than placebo group (P = 0.00, 0.01 and 0.04, respectively).
Effect
Neutral
Effect size
Small
Significant
No
Dose
100 U
Comparison of the Effect of Ceratonia siliqua L. (Carob) Syrup and Vitamin E on Sperm Parameters, Oxidative Stress Index, and Sex Hormones in Infertile Men: a Randomized Controlled Trial.
- 2020-09-21
- RCT · n = 60
- Reproductive sciences (Thousand Oaks, Calif.) 28(3)
- - Mir Mohammad Reza Aghajani
  - Soleiman Mahjoub
  - Soleiman Mahjoub
  - Faraz Mojab
  - Mahshid Namdari
  - Neda Mahdinezhad Gorji
  - Afsaneh Dashtaki
  - Parvaneh Mirabi
- PubMed: 32959223
- DOI: 10.1007/s43032-020-00314-3
7 Insights on
- Improved Sperm Motility
- High evidence
- Clinical
motility parameters (p = 0.002 Cohen's d = .90) were significantly higher in the carob group
Effect
Neutral
Effect size
Small
Significant
No
Dose
100 mg twice a day