Vitamin E and Improved White Matter Structural Protection

• Shifting Perspectives on the Role of Tocotrienol vs. Tocopherol in Brain Health: A Scoping Review.

  • 2025-06-30
  • Systematic Review
  • International journal of molecular sciences 26(13)
  • • Rabiatul Adawiyah Razali
    • Wan Zurinah Wan Ngah
    • Suzana Makpol
    • Daijiro Yanagisawa
    • Tomoko Kato
    • Ikuo Tooyama

  • PubMed: 40650110
  • DOI: 10.3390/ijms26136339

  1 Insight on

  • Improved White Matter Structural Protection

  • High evidence
  • Rigorous Journal

  Despite tocotrienol's lower plasma bioavailability, tocotrienol availability in selective brain regions has been associated with structural protection, particularly in white matter.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes