Vitamin E and Reduced Cardiac Event

• Pharmacological interventions to prevent cardiotoxicity in patients undergoing anthracycline-based chemotherapy: a network meta-analysis.

  • 2025-09-03
  • Systematic Review · n = 858
  • Frontiers in cardiovascular medicine 12
  • • Xiaoyu Liu
    • Ran Ding
    • Aihua Zhang

  • PubMed: 40970189
  • DOI: 10.3389/fcvm.2025.1612060

  1 Insight on

  • Reduced Cardiac Event

  • High evidence

  For reducing cardiac events, Dexrazoxane [OR = 0.28, 95% CI (0.16, 0.50)] and Vitamin E combined with Levocarnitine [OR = 0.27, 95% CI (0.08, 0.90)] were the most effective interventions.

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes