Comparative efficacy of febuxostat and vitamin E in the management of MASLD: Insights from a randomized parallel clinical study.
- 2025-08
- RCT · n = 32
- European journal of pharmacology 1000
- Hadier El-Sheikh
- Sahar El-Haggar
- Rehab Badawi
- Eslam Habba
- PubMed: 40383220
- DOI: 10.1016/j.ejphar.2025.177735
- High evidence
- Clinical
Both groups showed a significant reduction in CAP scores, with more pronounced decrease in vitamin E group (p < 0.001) compared to febuxostat group (p = 0.001).
- Effect
- Beneficial
- Effect size
- Large
- Significant
- Yes
- Dose
- 400 mg twice daily