Vitamin E and Reduced Seizure Frequency

• Efficacy and safety of vitamin E as adjunctive therapy for epilepsy: a systematic review and meta-analysis of randomized control trials.

  • 2025-07-11
  • Systematic Review · n = 824
  • Frontiers in neurology 16
  • • Yanfei Li
    • Gefei He
    • Juanjuan Huang
    • Lin Hu

  • PubMed: 40718099
  • DOI: 10.3389/fneur.2025.1628032

  4 Insights on

  • Reduced Seizure Frequency

  • High evidence
  • Clinical

  Vitamin E had a potential advantage in reducing seizure frequency by >75% (RR = 1.73, 95% confidence interval (CI) (1.31, 2.28), p < 0.01)

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes