Vitamin K and Reduced Dephosphorylated-Uncarboxylated Matrix Gla Protein Level

• Vitamin K supplementation and vascular calcification: a systematic review and meta-analysis of randomized controlled trials.

  • 2023-05-12
  • Systematic Review · n = 533
  • Frontiers in nutrition 10
  • • Te Li
    • Yun Wang
    • Wei-Ping Tu

  • PubMed: 37252246
  • DOI: 10.3389/fnut.2023.1115069

  2 Insights on

  • Reduced Dephosphorylated-Uncarboxylated Matrix Gla Protein Level

  • High evidence

  the study found that VK supplementation had a significant impact on dp-ucMGP levels, as compared to the control group, where those receiving VK supplementation had lower values [I² = 71%, MD = -243.31, 95% CI (-366.08, -120.53), p = 0.0001].

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes

  Dose

  not specified in abstract