Impact of supplemental vitamin K1 administration on postoperative blood component requirements after craniosynostosis repair: a prospective, placebo-controlled, randomized, blinded study.
- 2014-01-01
- RCT
- The Journal of craniofacial surgery 25(1)
- Jennifer S Kicker
- Douglas F Willson
- Robin L Kelly
- John A Jane
- Sarah E Roberts
- Mark R Conaway
- PubMed: 24406570
- DOI: 10.1097/scs.0000000000000384
- High evidence
- Infants
Elevated serum vitamin K1 levels at 6, 12, and 24 hours in the active drug group (P < 0.0001) were not associated with increased factor VII levels
- Effect
- Neutral
- Effect size
- Small
- Significant
- No