The effect of vitamin K1 supplementation on sensitivity and insulin resistance via osteocalcin in prediabetic women: a double-blind randomized controlled clinical trial.
- 2015-03-18
- RCT · n = 43
- European journal of clinical nutrition 69(8)
- H Rasekhi
- M Karandish
- M T Jalali
- M Mohammad-Shahi
- M Zarei
- A Saki
- H Shahbazian
- PubMed: 25782427
- DOI: 10.1038/ejcn.2015.17
- High evidence
- Rigorous Journal
- Clinical
Phylloquinone supplementation increased the serum levels of cOC and decreased ucOC, compared with placebo (12.53 ± 5.95 compared with 7.43 ± 4.85 ng/ml and 2.47 ± 1.91 compared with 4.79 ± 2.43 ng/ml, respectively; P < 0.001).
- Effect
- Beneficial
- Effect size
- Large
- Significant
- Yes
- Dose
- 1000 μg/day