Six months vitamin K treatment does not affect systemic arterial calcification or bone mineral density in diabetes mellitus 2.
- 2020-10-17
- RCT · n = 68
- European journal of nutrition 60(3)
- Jonas W Bartstra
- Fieke Draaisma
- Sabine R Zwakenberg
- Nikolas Lessmann
- Jelmer M Wolterink
- Yvonne T van der Schouw
- Pim A de Jong
- Joline W J Beulens
- PubMed: 33068157
- DOI: 10.1007/s00394-020-02412-z
- High evidence
- Rigorous Journal
- Clinical
Six months vitamin K2 supplementation did not reduce arterial calcification progression (β [95% CI]: - 0.02 [- 0.10; 0.06] for the total arterial calcification mass) when compared to placebo.
- Effect
- Neutral
- Effect size
- Small
- Significant
- No
- Dose
- 360 µg/day