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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Vitamin K2 and Reduced Vascular Stiffness

Doses used in studies

mcg/day: 180 (median 180, IQR 180–180) — 1 study

Time to effect

Median: 12.2 months · IQR 12.2 months–12.2 months · Range 12.2 months–12.2 months — Reported in 1 of 1 study

1 of 1 paper

Effects of One-Year Menaquinone-7 Supplementation on Vascular Stiffness and Blood Pressure in Post-Menopausal Women.
- 2025-02-27
- RCT · n = 165
- Nutrients 17(5)
- - Femke de Vries
  - Rudolf Bittner
  - Katarzyna Maresz
  - François Machuron
  - Olav Gåserød
  - Jean-François Jeanne
  - Leon J Schurgers
- PubMed: 40077685
- DOI: 10.3390/nu17050815
3 Insights on
- Reduced Vascular Stiffness
- High evidence
- Large Human Trial
- Rigorous Journal
- Clinical
MK-7 treatment significantly attenuated vascular stiffness in post-menopausal women (placebo +49.1% ± 77.4; MK-7 +9.4% ± 67.1; p = 0.035).
Effect
Beneficial
Effect size
Moderate
Significant
Yes
Dose
180 µg daily