Astaxanthin and Reduced Follicular Fluid Cell-Free DNA Level

Doses used in studies

mg/day: 12 (median 12, IQR 12–12) — 1 study

Time to effect

Median: 8 weeks · IQR 8 weeks–8 weeks · Range 8 weeks–8 weeks — Reported in 1 of 1 study

1 of 1 paper

Astaxanthin improves assisted reproductive technology outcomes in poor ovarian responders through alleviating oxidative stress, inflammation, and apoptosis: a randomized clinical trial.

2024-10-31
RCT
Journal of ovarian research 17(1)
- Anahid Shafie
- Ashraf Aleyasin
- Mojtaba Saffari
- Mojtaba Saedi
- Sahar Rostami
- Saeede Rezayi
- Seyed Danial Mohammadi
- Fardin Amidi

PubMed: 39482765
DOI: 10.1186/s13048-024-01537-7

12 Insights on

Reduced Follicular Fluid Cell-Free DNA Level

High evidence
Clinical

In the AST group, FF levels of IL-6 (P=0 < 001), IL-8 (P=0.036), VEGF (P=0.006), and cfDNA (P<0.001) were significantly lower than in the placebo group.

Effect: Beneficial
Effect size: Small
Significant: Yes
Dose: 12 mg/day