Effects of replacing solid fats and added sugars with avocado in adults with elevated cardiometabolic risk: a randomized, double-blind, controlled feeding, crossover trial.
- 2026-02
- RCT
- The American journal of clinical nutrition 123(2)
- Nana Gletsu-Miller
- Meredith L Wilcox
- Lisa A Spence
- Amy J Wright
- Liana L Guarneiri
- Muhammad M Nadeem
- Mark J Hutter
- Karen L Sprague
- Andrew W Brown
- Allon N Friedman
- Carol F Kirkpatrick
- Kevin C Maki
- PubMed: 41397527
- DOI: 10.1016/j.ajcnut.2025.101137
- High evidence
- Clinical
An intention-to-treat analysis showed significantly larger percentage changes, 95% confidence intervals (CIs), from baseline after the avocado condition, compared with after the control condition, for ... small low-density lipoprotein subfraction cholesterol (-13.9%; 95% CI: -23.2%, -3.49%; P = 0.012)
- Effect
- Beneficial
- Effect size
- Small
- Significant
- Yes
- Dose
- 1 avocado (∼180 g/d, ∼300 kcal/d)