avocado and Reduced Systolic Blood Pressure

Research synthesisLow evidenceSmall effect3 studies · 2 beneficial · 1 neutral · 0 harmful

Across 3 studies, 2 reported small beneficial effects on systolic blood pressure, while 1 reported a neutral effect. The most studied dose was 1 avocado daily. Effects were observed in clinical populations (abdominal obesity, elevated triglycerides) with a median study duration of 101 days.

Effective dose range: 1 avocado daily
Studied populations: Adults with abdominal obesity or elevated triglycerides

Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. One short-term study (21 days) found no significant effect, while longer-term studies (180 days) and a meta-analysis showed small benefits. The clinical significance of a ~1.15 mmHg reduction is uncertain.

Generated Jul 10, 2026

Doses used in studies

avocado/day: 1 (median 1, IQR 1–1) — 1 study
g/day: 180 (median 180, IQR 180–180) — 1 study

Time to effect

Median: 3.4 months · IQR 8.7 weeks–4.7 months · Range 3 weeks–6 months — Reported in 2 of 3 studies

3 of 3 papersPopulation:

Serum Metabolite Profiles in Adults With Abdominal Obesity in Response to Consuming 1 Avocado Daily for 6 Months: An Exploratory Analysis.
- 2026-03-13
- RCT · n = 120
- Journal of the American Heart Association 15(6)
- - Nirupa R Matthan
  - Ecaterina Duscova
  - Gregory Matuszek
  - Wen Zhang
  - Penny M Kris-Etherton
  - Kristina S Petersen
  - Sujatha Rajaram
  - Zhaoping Li
  - David M Reboussin
  - Joan Sabate
  - Alice H Lichtenstein
- PubMed: 41823253
- DOI: 10.1161/jaha.125.044144
4 Insights on
- Reduced Systolic Blood Pressure
- High evidence
- Large Human Trial
- Clinical
systolic (-3%) ... decreased
Effect
Beneficial
Effect size
Small
Significant
Yes
Dose
1 avocado daily
Effects of replacing solid fats and added sugars with avocado in adults with elevated cardiometabolic risk: a randomized, double-blind, controlled feeding, crossover trial.
- 2026-02
- RCT
- The American journal of clinical nutrition 123(2)
- - Nana Gletsu-Miller
  - Meredith L Wilcox
  - Lisa A Spence
  - Amy J Wright
  - Liana L Guarneiri
  - Muhammad M Nadeem
  - Mark J Hutter
  - Karen L Sprague
  - Andrew W Brown
  - Allon N Friedman
  - Carol F Kirkpatrick
  - Kevin C Maki
- PubMed: 41397527
- DOI: 10.1016/j.ajcnut.2025.101137
12 Insights on
- Reduced Systolic Blood Pressure
- High evidence
- Clinical
Percentage changes for other lipoprotein lipids, glucose, insulin, and blood pressures did not significantly differ (P > 0.05) between conditions.
Effect
Neutral
Effect size
Small
Significant
No
Dose
1 avocado (∼180 g/d, ∼300 kcal/d)
Effects of Avocado Products on Cardiovascular Risk Factors in Adults: A GRADE-Assessed Systematic Review and Meta-Analysis.
- 2025-07-02
- Review
- Food science & nutrition 13(7)
- - Sahel Hamednia
  - Zahra Shouhani
  - Sara Tavakol
  - Nazanin Montazeri
  - Mohammadreza Amirkhan-Dehkordi
  - Mohammad Amin Karimi
  - Mehraveh Bastamkhani
  - Haleh Chavoshian Tabrizy
  - Ramin Amirsasan
  - Javad Vakili
  - Mehdi Karimi
  - Omid Asbaghi
- PubMed: 40612140
- DOI: 10.1002/fsn3.70547
9 Insights on
- Reduced Systolic Blood Pressure
- Low evidence
- Adults
a significant reduction was observed in systolic blood pressure (BP) (WMD: -1.15 mmHg; p=0.03; I2=56%)
Effect
Beneficial
Effect size
Small
Significant
Yes

avocado and Reduced Systolic Blood Pressure

Serum Metabolite Profiles in Adults With Abdominal Obesity in Response to Consuming 1 Avocado Daily for 6 Months: An Exploratory Analysis.

Effects of replacing solid fats and added sugars with avocado in adults with elevated cardiometabolic risk: a randomized, double-blind, controlled feeding, crossover trial.

Effects of Avocado Products on Cardiovascular Risk Factors in Adults: A GRADE-Assessed Systematic Review and Meta-Analysis.