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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Chicory and Improved Global Assessment

Doses used in studies

mg/day: 600–1,800 (median 1,200, IQR 600–1,800) — 1 study

Time to effect

Median: 4.3 weeks · IQR 4.3 weeks–4.3 weeks · Range 4.3 weeks–4.3 weeks — Reported in 1 of 1 study

Safety in these studies

Overall tolerabilityReported
In general, the treatment was well-tolerated.
from: Phase 1, placebo-controlled, dose escalation trial of chicory root extract in patients wit

1 of 1 paper

Phase 1, placebo-controlled, dose escalation trial of chicory root extract in patients with osteoarthritis of the hip or knee.
- 2010-07-09
- RCT · n = 40
- BMC musculoskeletal disorders 11(1)
- - Nancy J Olsen
  - Valerie K Branch
  - Geetha Jonnala
  - Mira Seskar
  - Melisa Cooper
- PubMed: 20618964
- DOI: 10.1186/1471-2474-11-156
4 Insights on
- Improved Global Assessment
- High evidence
- Clinical
13 patients showed at least 20% improvement in the defined response domains of pain, stiffness and global assessment: 9 of 10 (90%) patients randomized to active treatment with chicory and 4 of 8 (50%) patients randomized to placebo (P = 0.06).
Effect
Neutral
Effect size
Small
Significant
No
Dose
1800 mg/day